Depakote (Divalproex)

Depakote is a seizure medication that is used for treating a broad range of seizure disorders.

Depakote 500 mg (Normal Dosage)

Package Price Savings Order
30 pills
Only $2.28 Per Pill
Add to cart
60 pills
Only $1.97 Per Pill
$18.73 Add to cart
90 pills
Only $1.70 Per Pill
$52.40 Add to cart

Depakote 250 mg (Low Dosage)

Package Price Savings Order
30 pills
Only $1.35 Per Pill
Add to cart
60 pills
Only $1.17 Per Pill
$11.13 Add to cart
90 pills
Only $1.04 Per Pill
$28.14 Add to cart
How it works

Depakote works by affecting certain chemicals in the body that cause seizures.

Guidelines for usage

Follow the dosage instructions provided by your doctor or as mentioned in the instruction booklet/product label.

Always use only as prescribed. Never exceed the dosage.

Depakote may be used with or without food.

Doctors recommend that you swallow the whole tablet/capsules with a glass of water unless it is specified that it can be broken or chewed.

NOTE: Use only if prescribed to you and intended for your use. Do not share with others.

Missed Dose

It is common for people to forget their dosage times and miss doses.

Do not panic if you have missed a dose.

Instead, skip the missed dose and take your next dose at the scheduled time. Do not double up or take more than what the doctor has prescribed.

How & where do I store Depakote?

The medicine label contains detailed instructions regarding safe storage of the medication. Most medicines are best stored at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Some medications may require to be refrigerated. Please check the product label.

Keep it away from the reach of children. Ensure that it is not exposed to direct sunlight or moisture.

Ask your pharmacist about safely disposing off medication that is past expiry date.

Overdose Related Information

If you accidentally consume more medication than what was prescribed, then contact an emergency healthcare center immediately.
Safety Information/ Warning Precautions

Discuss your medical history with your healthcare provider before you start using any new medication.

Ensure that you mention the following:

Any prior serious ailment, lifestyle disease or surgery
All the prescription drugs, OTC health supplements, herbal supplements that you are using currently
Your alcohol intake and whether you smoke or not
Any history of a known allergic reaction to prescription drugs or food
Liver disease;
A bleeding or blood clotting disorder;
A history of head injury, brain disorder, or coma;
A family history of a urea cycle disorder or infant deaths with unknown cause; or
Hiv or cmv (cytomegalovirus) infection.

This will allow your healthcare provider to prescribe the apt dosage of the medication for you.

Using Alcohol

Depakote is known to cause drowsiness or dizziness. Your vision may be blurred and your judgement affected if you consume alcohol with this medication. So, avoid using alcohol while using Depakote.

These effects may also get aggravated due to hot weather or fever or severe exercise. So, be cautious when you stand up after a long time from a sitting or lying position. If you feel giddy then lie down immediately and seek medical help.

Possible Drug & Food Interactions

Certain prescription drugs or health supplements or even food items are known to interact with the effects of medications. Depakote is known to have possible interactions with the following medications.

Additional Information

If one notices symptoms like nausea, vomiting, upper stomach pain, or loss of appetite, low fever, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes), then it must be reported immediately to the doctor because it could be symptoms of liver damage.

Mood and behavior changes and depression etc should also be reported promptly to the doctor.

It may increase suicidal thoughts in patients.

If your doctor has prescribed laboratory tests then ensure that you do not miss out on them.

Elderly people are more likely to experience side effects while using Depakote. If the side effects are bothersome, then seek medical help.

Depakote has been associated with fatal liver failure in children below 2 years of age. So, if the patient is under this age, then speak to your doctor regarding the possible risks.

Important Information for Pregnant Women

Depakote is categorized under FDA pregnancy category D.

Discuss the potential risks with your healthcare provider before using the medication.

Certain medications may be found in breast milk so speak to your child’s doctor to rule out any possibilities of risk.
Side Effects

Report the following side effects to your doctor only if they become bothersome or do not stop on their own

Mild drowsiness or weakness;
Diarrhea, constipation, upset stomach;
Changes in your menstrual periods;
Enlarged breasts, weight changes;
Tremor (shaking);
Hair loss;
Vision changes; or
Unusual or unpleasant taste in your mouth

The following side effects require immediate medical attention. So report these to your doctor immediately.

Unexplained weakness with vomiting and confusion or fainting;
Easy bruising or bleeding, blood in your urine;
Fever, chills, body aches, swollen glands, flu symptoms;
Urinating less than usual;
Extreme drowsiness, lack of coordination, hallucinations;
Double vision or back-and-forth movements of the eyes; or
Severe skin reaction - fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.